Oak Knoll is the southernmost neighborhood in Pasadena. It is bordered by Oak Knoll Circle to the north, Old Mill Road to the south, South Oak Knoll Avenue and South Oakland Avenue to the west, and the San Marino border (Kewen Drive and Encino Drive) to the east. The Oak Knoll Neighborhood encompasses 397 single family residences and the historic Langham Huntington Hotel.

This upscale neighborhood on rolling, oak covered terrain, was developed in 1905 by a corporate partnership between prominent Northeastern United States and California residents A. Kingsley Macomber, Henry E. Huntington and William R. Staats.

Building continued through the 1920's and Oak Knoll’s exclusive status attracted wealthy residents who could afford prestigious architects. Oak Knoll features homes by Wallace Neff, the Heineman brothers, George Washington Smith, Roland Coate, Gordon Kaufmann, Reginald Johnson and Marston & Van Pelt.